Research » Brain Damage » This paper from Psychoneuroendocrinology (Volume 74, December 2016, Pages 371-379) reports on subcortical gray matter changes in transgender subjects after long-term cross-sex hormone administration. Assessing the influence of high-dose cross-sex hormone administration on the brain. Inclusion of transgender participants undergoing hormonal treatment. Subcortical brain changes in areas related to cognition and emotion. Changes in progesterone