In a recent paper from 1st December 2021, four endocrinologists lent their name to the recommendation that: “adolescents should not be given testosterone to treat gender incongruence under any circumstances because of these factors.”
Note: These are links to articles, research papers and testimonials. Some resources are duplicated.
Heart Disease , Including Both Atherosclerosis And Heart Tissue Damage
Vaginal Atrophy (Burning, Itching, Painful Intercourse, Discharge)
Pelvic Pain Leading to Hysterectomy
Babies Born With Birth Defects Including Blindness And Club Feet
Violent Mood Swings, From Euphoria To Rage
Worsening of Underlying Manic or Psychotic Conditions
Persistent Hoarseness And Loss of Voice Projection
Headaches and Visual Disturbances
This list of known side-effects of testosterone is not exhaustive. Furthermore, there are likely to be more sources of good evidence coming to light all the time. Please let us know if you find something of interest, and we shall update this reference.
Further reading:
The widespread use of testosterone to dope female athletes in East Germany in the 1980’s means that there is longitudinal evidence of the catastrophic harm done by giving large doses of male hormones to females:
See also: Faust’s Gold: Inside the East German Doping Machine by Steven Ungerleider